Publicaciones

Glyco-checkpoints e inmunosupresión tumoral
Glyco-checkpoints en fenómenos de vascularización
Cáncer colorrectal (CCR)
Adenocarcinoma ductal de páncreas (PDAC)
Cáncer de mama
Glioblastoma
Cáncer de hígado
Cáncer renal
Cáncer de pulmón
Cáncer de piel
Autoinmunidad e inflamación
Autoinmunidad e inflamaciónGlyco-checkpoints e inmunosupresión tumoralGlyco-checkpoints en fenómenos de vascularizaciónTodas

Glycan-Binding Proteins in Immunity

Rabinovich GA, et al - Annu Rev Immunol. 2026 Apr
Adenocarcinoma ductal de páncreas (PDAC)

Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells

Cagnoni AJ, et al - Proc Natl Acad Sci U S A. 2021 May
Glyco-checkpoints e inmunosupresión tumoral

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1...

Li R, et al - Sci Transl Med. 2024 Oct
Glyco-checkpoints en fenómenos de vascularización

Circulating galectin-1 delineates response to bevacizumab in melanoma patients and reprograms...

Bannoud N, et al - Proc Natl Acad Sci U S A. 2023 Jan
Glyco-checkpoints e inmunosupresión tumoral

Targeting galectin-driven regulatory circuits in cancer and fibrosis

Mariño KV, et al - Nat Rev Drug Discov. 2023 Apr

Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

Pinto NA, et al - Cell Death Differ. 2023 Apr
Autoinmunidad e inflamación

Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm

Roldán-Montero R, et al - Sci Adv. 2022 Mar
Cáncer colorrectal (CCR)

Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8+...

Cagnoni AJ, et al - Proc Natl Acad Sci U S A. 2021 May
Autoinmunidad e inflamación

Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits

Morosi LG, et al - Sci Adv. 2021 Jun
Autoinmunidad e inflamación

Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a...

Russo AJ, et al - Nat Immunol. 2021 Feb
Autoinmunidad e inflamación

Suppression of age-related salivary gland autoimmunity by glycosylation-dependent galectin-1-driven immune inhibitory...

Martínez Allo VC, et al - Proc Natl Acad Sci U S A. 2020 Mar

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune...

Segovia M, et al - Cancer Cell. 2019 May
Glyco-checkpoints e inmunosupresión tumoral

IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial...

Song M, et al - Nature. 2018 Oct
Adenocarcinoma ductal de páncreas (PDAC)

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk

Orozco CA, et al - Proc Natl Acad Sci U S A. 2018 Apr
Cáncer de mama

Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation

Rutkowski MR, et al - Cancer Cell. 2015 Jan

Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease

Dalotto-Moreno T, et al - Cancer Res. 2013
Glyco-checkpoints e inmunosupresión tumoral

A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1...

Laderach DJ, etc al - Cancer Res. 2013 Jan
Autoinmunidad e inflamación

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

Rabinovich GA, Croci DO. - Immunity. 2012 Mar
Autoinmunidad e inflamación

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

Starossom SC, et al - Immunity. 2012 Aug
Cáncer de piel

Tolerogenic signals delivered by dendritic cells to T cells through a...

Ilarregui JM, et al - Nat Immunol. 2009 Sep
Autoinmunidad e inflamación

A pivotal role for galectin-1 in fetomaternal tolerance

Blois SM, et al - Nat Med. 2007 Dec
Autoinmunidad e inflamación

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates...

Toscano MA, et al - Nat Immunol. 2007 Aug

Targeted inhibition of galectin-1 gene expression in tumor cells results in...

Rubinstein N, et al - Cancer Cell. 2004 Mar
PublicacionesTodas

Regulated expression of a 16-kd galectin-like protein in activated rat macrophages

Rabinovich, G et al. Journal of leukocyte biology vol. 59,3 (1996)